SR45-downregulated; refined

Genes269
GO terms484
Edges:1858
Max GO term frequency:94
Average annotation per gene:6
Generic GO terms (BLUE):33
GO terms not selected in topics (MAGENTA):361
Count of eliminated edges:512
GO terms occurring in topics:90
Topics threshold:0.05


GO terms occurring in more than one topic and having score >= the threshold at least in one topic (31):

GOGO frequencyTopics
Interest Eliminate   |    GO:0005886--plasma membrane 9011   (0, 1, 5, 9, 13, 14, 16, 22, 26, 28, 29)
Interest Eliminate   |    GO:0005524--atp binding 556   (2, 4, 9, 14, 26, 28)
Interest Eliminate   |    GO:0005829--cytosol 145   (0, 2, 19, 20, 23)
Interest Eliminate   |    GO:0005794--golgi apparatus 114   (0, 3, 11, 17)
Interest Eliminate   |    GO:0055114--oxidation-reduction process 214   (12, 14, 19, 23)
Interest Eliminate   |    GO:0004672--protein kinase activity 253   (26, 28, 29)
Interest Eliminate   |    GO:0005509--calcium ion binding 113   (2, 17, 27)
Interest Eliminate   |    GO:0005618--cell wall 103   (0, 18, 19)
Interest Eliminate   |    GO:0005773--vacuole 113   (9, 19, 29)
Interest Eliminate   |    GO:0009507--chloroplast 223   (3, 4, 13)
Interest Eliminate   |    GO:0003677--dna binding 132   (6, 10)
Interest Eliminate   |    GO:0004674--protein serine/threonine kinase activity 372   (26, 28)
Interest Eliminate   |    GO:0005739--mitochondrion 212   (11, 25)
Interest Eliminate   |    GO:0006351--transcription, dna-templated 182   (6, 10)
Interest Eliminate   |    GO:0006355--regulation of transcription, dna-templated 182   (6, 10)
Interest Eliminate   |    GO:0006468--protein phosphorylation 402   (26, 28)
Interest Eliminate   |    GO:0006508--proteolysis 82   (18, 22)
Interest Eliminate   |    GO:0006952--defense response 342   (4, 5)
Interest Eliminate   |    GO:0006979--response to oxidative stress 92   (16, 23)
Interest Eliminate   |    GO:0009505--plant-type cell wall 72   (0, 27)
Interest Eliminate   |    GO:0012501--programmed cell death 42   (18, 29)
Interest Eliminate   |    GO:0043531--adp binding 72   (4, 5)
Interest Eliminate   |    GO:0043565--sequence-specific dna binding 92   (6, 10)
Interest Eliminate   |    GO:0046872--metal ion binding 162   (7, 23)


Frequency of GO terms that are eliminated (BLUE 33) or not selected in topics (MAGENTA 94 with frequency >=2):

GOGO frequency
Interest    Eliminate   |    GO:0016021--integral component of membrane 94
Interest    Eliminate   |    GO:0005634--nucleus 61
Interest    Eliminate   |    GO:0016301--kinase activity 49
Interest    Eliminate   |    GO:0005576--extracellular region 47
Interest    Eliminate   |    GO:0003674--molecular_function 40
Interest    Eliminate   |    GO:0008150--biological_process 37
Interest    Eliminate   |    GO:0005737--cytoplasm 35
Interest    Eliminate   |    GO:0016020--membrane 24
Interest    Eliminate   |    GO:0003700--transcription factor activity, sequence-specific DNA binding 22
Interest    Eliminate   |    GO:0005515--protein binding 19
Interest    Eliminate   |    GO:0048046--apoplast 14
Interest    Eliminate   |    GO:0030246--carbohydrate binding 12
Interest    Eliminate   |    GO:0005575--cellular_component 10
Interest    Eliminate   |    GO:0019825--oxygen binding 10
Interest    Eliminate   |    GO:0016787--hydrolase activity 9
Interest    Eliminate   |    GO:0005783--endoplasmic reticulum 6
Interest    Eliminate   |    GO:0009626--plant-type hypersensitive response 6
Interest    Eliminate   |    GO:0016310--phosphorylation 5
Interest    Eliminate   |    GO:0009682--induced systemic resistance 4
Interest    Eliminate   |    GO:0009816--defense response to bacterium, incompatible interaction 4
Interest    Eliminate   |    GO:0009873--ethylene-activated signaling pathway 4
Interest    Eliminate   |    GO:0042626--ATPase activity, coupled to transmembrane movement of substances 4
Interest    Eliminate   |    GO:0046686--response to cadmium ion 4
Interest    Eliminate   |    GO:0048544--recognition of pollen 4
Interest    Eliminate   |    GO:0052544--defense response by callose deposition in cell wall 4
Interest    Eliminate   |    GO:0055085--transmembrane transport 4
Interest    Eliminate   |    GO:0080167--response to karrikin 4
Interest    Eliminate   |    GO:0000325--plant-type vacuole 3
Interest    Eliminate   |    GO:0002229--defense response to oomycetes 3
Interest    Eliminate   |    GO:0004497--monooxygenase activity 3
Interest    Eliminate   |    GO:0004553--hydrolase activity, hydrolyzing O-glycosyl compounds 3
Interest    Eliminate   |    GO:0004675--transmembrane receptor protein serine/threonine kinase activity 3
Interest    Eliminate   |    GO:0005215--transporter activity 3
Interest    Eliminate   |    GO:0005351--sugar:proton symporter activity 3
Interest    Eliminate   |    GO:0005622--intracellular 3
Interest    Eliminate   |    GO:0008559--xenobiotic-transporting ATPase activity 3
Interest    Eliminate   |    GO:0009611--response to wounding 3
Interest    Eliminate   |    GO:0009620--response to fungus 3
Interest    Eliminate   |    GO:0009753--response to jasmonic acid 3
Interest    Eliminate   |    GO:0015144--carbohydrate transmembrane transporter activity 3
Interest    Eliminate   |    GO:0030154--cell differentiation 3
Interest    Eliminate   |    GO:0031625--ubiquitin protein ligase binding 3
Interest    Eliminate   |    GO:0046777--protein autophosphorylation 3
Interest    Eliminate   |    GO:0071446--cellular response to salicylic acid stimulus 3
Interest    Eliminate   |    GO:0000139--Golgi membrane 2
Interest    Eliminate   |    GO:0000151--ubiquitin ligase complex 2
Interest    Eliminate   |    GO:0000165--MAPK cascade 2
Interest    Eliminate   |    GO:0000210--NAD+ diphosphatase activity 2
Interest    Eliminate   |    GO:0000981--RNA polymerase II transcription factor activity, sequence-specific DNA binding 2
Interest    Eliminate   |    GO:0001135--transcription factor activity, RNA polymerase II transcription factor recruiting 2
Interest    Eliminate   |    GO:0003723--RNA binding 2
Interest    Eliminate   |    GO:0004190--aspartic-type endopeptidase activity 2
Interest    Eliminate   |    GO:0004364--glutathione transferase activity 2
Interest    Eliminate   |    GO:0004601--peroxidase activity 2
Interest    Eliminate   |    GO:0004806--triglyceride lipase activity 2
Interest    Eliminate   |    GO:0005216--ion channel activity 2
Interest    Eliminate   |    GO:0005355--glucose transmembrane transporter activity 2
Interest    Eliminate   |    GO:0005525--GTP binding 2
Interest    Eliminate   |    GO:0005578--proteinaceous extracellular matrix 2
Interest    Eliminate   |    GO:0005623--cell 2
Interest    Eliminate   |    GO:0005802--trans-Golgi network 2
Interest    Eliminate   |    GO:0006357--regulation of transcription from RNA polymerase II promoter 2
Interest    Eliminate   |    GO:0006457--protein folding 2
Interest    Eliminate   |    GO:0006470--protein dephosphorylation 2
Interest    Eliminate   |    GO:0006623--protein targeting to vacuole 2
Interest    Eliminate   |    GO:0006825--copper ion transport 2
Interest    Eliminate   |    GO:0006855--drug transmembrane transport 2
Interest    Eliminate   |    GO:0007169--transmembrane receptor protein tyrosine kinase signaling pathway 2
Interest    Eliminate   |    GO:0007623--circadian rhythm 2
Interest    Eliminate   |    GO:0008219--cell death 2
Interest    Eliminate   |    GO:0008375--acetylglucosaminyltransferase activity 2
Interest    Eliminate   |    GO:0009055--electron carrier activity 2
Interest    Eliminate   |    GO:0009407--toxin catabolic process 2
Interest    Eliminate   |    GO:0009409--response to cold 2
Interest    Eliminate   |    GO:0009624--response to nematode 2
Interest    Eliminate   |    GO:0009625--response to insect 2
Interest    Eliminate   |    GO:0009684--indoleacetic acid biosynthetic process 2
Interest    Eliminate   |    GO:0009697--salicylic acid biosynthetic process 2
Interest    Eliminate   |    GO:0009738--abscisic acid-activated signaling pathway 2
Interest    Eliminate   |    GO:0009759--indole glucosinolate biosynthetic process 2
Interest    Eliminate   |    GO:0009817--defense response to fungus, incompatible interaction 2
Interest    Eliminate   |    GO:0009826--unidimensional cell growth 2
Interest    Eliminate   |    GO:0009863--salicylic acid mediated signaling pathway 2
Interest    Eliminate   |    GO:0009867--jasmonic acid mediated signaling pathway 2
Interest    Eliminate   |    GO:0009908--flower development 2
Interest    Eliminate   |    GO:0009910--negative regulation of flower development 2
Interest    Eliminate   |    GO:0009941--chloroplast envelope 2
Interest    Eliminate   |    GO:0010193--response to ozone 2
Interest    Eliminate   |    GO:0010197--polar nucleus fusion 2
Interest    Eliminate   |    GO:0016491--oxidoreductase activity 2
Interest    Eliminate   |    GO:0016705--oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2
Interest    Eliminate   |    GO:0016798--hydrolase activity, acting on glycosyl bonds 2
Interest    Eliminate   |    GO:0017119--Golgi transport complex 2
Interest    Eliminate   |    GO:0019761--glucosinolate biosynthetic process 2
Interest    Eliminate   |    GO:0030091--protein repair 2
Interest    Eliminate   |    GO:0030551--cyclic nucleotide binding 2
Interest    Eliminate   |    GO:0031012--extracellular matrix 2
Interest    Eliminate   |    GO:0031347--regulation of defense response 2
Interest    Eliminate   |    GO:0031348--negative regulation of defense response 2
Interest    Eliminate   |    GO:0033743--peptide-methionine (R)-S-oxide reductase activity 2
Interest    Eliminate   |    GO:0035428--hexose transmembrane transport 2
Interest    Eliminate   |    GO:0042391--regulation of membrane potential 2
Interest    Eliminate   |    GO:0042542--response to hydrogen peroxide 2
Interest    Eliminate   |    GO:0043231--intracellular membrane-bounded organelle 2
Interest    Eliminate   |    GO:0043295--glutathione binding 2
Interest    Eliminate   |    GO:0045087--innate immune response 2
Interest    Eliminate   |    GO:0045893--positive regulation of transcription, DNA-templated 2
Interest    Eliminate   |    GO:0046323--glucose import 2
Interest    Eliminate   |    GO:0047631--ADP-ribose diphosphatase activity 2
Interest    Eliminate   |    GO:0048527--lateral root development 2
Interest    Eliminate   |    GO:0050660--flavin adenine dinucleotide binding 2
Interest    Eliminate   |    GO:0051287--NAD binding 2
Interest    Eliminate   |    GO:0051865--protein autoubiquitination 2
Interest    Eliminate   |    GO:0061630--ubiquitin protein ligase activity 2
Interest    Eliminate   |    GO:1900057--positive regulation of leaf senescence 2
Interest    Eliminate   |    GO:1900150--regulation of defense response to fungus 2
Interest    Eliminate   |    GO:2001147--camalexin binding 2
Interest    Eliminate   |    GO:2001227--quercitrin binding 2
Interest    Eliminate   |    GO:0003682--chromatin binding 1
Interest    Eliminate   |    GO:0003824--catalytic activity 1
Interest    Eliminate   |    GO:0004871--signal transducer activity 1
Interest    Eliminate   |    GO:0005615--extracellular space 1
Interest    Eliminate   |    GO:0005911--cell-cell junction 1
Interest    Eliminate   |    GO:0016740--transferase activity 1
Interest    Eliminate   |    GO:0040008--regulation of growth 1
Interest    Eliminate   |    GO:0043234--protein complex 1
Interest    Eliminate   |    GO:0071554--cell wall organization or biogenesis 1


All Topics:

Topic #0: Interesting topic
Score: 0.0814GO:0005618--cell wall
Score: 0.0679GO:0005886--plasma membrane
Score: 0.0544GO:0005794--golgi apparatus
Score: 0.0544GO:0009505--plant-type cell wall
Score: 0.0274GO:0005829--cytosol
GO terms cooccurrence

Topic #1: Interesting topic
Score: 0.0510GO:0005886--plasma membrane
Score: 0.0383GO:0031225--anchored component of membrane
Score: 0.0383GO:0016757--transferase activity, transferring glycosyl groups
Score: 0.0257GO:0042742--defense response to bacterium
Score: 0.0257GO:0009651--response to salt stress
GO terms cooccurrence

Topic #2: Interesting topic
Score: 0.0954GO:0005509--calcium ion binding
Score: 0.0796GO:0030247--polysaccharide binding
Score: 0.0480GO:0007166--cell surface receptor signaling pathway
Score: 0.0322GO:0005829--cytosol
Score: 0.0238GO:0005524--atp binding
GO terms cooccurrence

Topic #3: Interesting topic
Score: 0.1929GO:0009507--chloroplast
Score: 0.0740GO:0071456--cellular response to hypoxia
Score: 0.0496GO:0006897--endocytosis
Score: 0.0496GO:0005901--caveola
Score: 0.0252GO:0005794--golgi apparatus
GO terms cooccurrence

Topic #4: Interesting topic
Score: 0.1458GO:0043531--adp binding
Score: 0.0733GO:0005524--atp binding
Score: 0.0550GO:0006952--defense response
Score: 0.0491GO:0009507--chloroplast
Score: 0.0250GO:0005788--endoplasmic reticulum lumen
GO terms cooccurrence

Topic #5: Interesting topic
Score: 0.4048GO:0006952--defense response
Score: 0.2725GO:0007165--signal transduction
Score: 0.0654GO:0005886--plasma membrane
Score: 0.0156GO:0055046--microgametogenesis
Score: 0.0005GO:0043531--adp binding
GO terms cooccurrence

Topic #6: Interesting topic
Score: 0.1504GO:0006355--regulation of transcription, dna-templated
Score: 0.1409GO:0006351--transcription, dna-templated
Score: 0.1134GO:0003677--dna binding
Score: 0.0568GO:0043565--sequence-specific dna binding
Score: 0.0474GO:0044212--transcription regulatory region dna binding
GO terms cooccurrence

Topic #7: Interesting topic
Score: 0.1254GO:0007275--multicellular organism development
Score: 0.0257GO:0004842--ubiquitin-protein transferase activity
Score: 0.0257GO:0016567--protein ubiquitination
Score: 0.0257GO:0010224--response to uv-b
Score: 0.0257GO:0046872--metal ion binding
GO terms cooccurrence

Topic #8: Interesting topic
Score: 0.0651GO:0009617--response to bacterium
Score: 0.0328GO:0009737--response to abscisic acid
Score: 0.0328GO:0042742--defense response to bacterium
Score: 0.0328GO:0009651--response to salt stress
Score: 0.0328GO:0009723--response to ethylene
GO terms cooccurrence

Topic #9: Interesting topic
Score: 0.1582GO:0009506--plasmodesma
Score: 0.1302GO:0005886--plasma membrane
Score: 0.0925GO:0005774--vacuolar membrane
Score: 0.0787GO:0005773--vacuole
Score: 0.0677GO:0005524--atp binding
GO terms cooccurrence

Topic #10: Interesting topic
Score: 0.1585GO:0009733--response to auxin
Score: 0.0017GO:0043565--sequence-specific dna binding
Score: 0.0017GO:0003677--dna binding
Score: 0.0017GO:0006351--transcription, dna-templated
Score: 0.0017GO:0006355--regulation of transcription, dna-templated
GO terms cooccurrence

Topic #11: Interesting topic
Score: 0.0414GO:0005794--golgi apparatus
Score: 0.0414GO:0046658--anchored component of plasma membrane
Score: 0.0414GO:0005739--mitochondrion
Score: 0.0210GO:0005975--carbohydrate metabolic process
Score: 0.0210GO:0051707--response to other organism
GO terms cooccurrence

Topic #12: Interesting topic
Score: 0.0632GO:0016709--oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, nad(p)h as one donor, and incorporation of one atom of oxygen
Score: 0.0632GO:0020037--heme binding
Score: 0.0626GO:0005506--iron ion binding
Score: 0.0624GO:0055114--oxidation-reduction process
Score: 0.0492GO:0044550--secondary metabolite biosynthetic process
GO terms cooccurrence

Topic #13: Interesting topic
Score: 0.0251GO:0005886--plasma membrane
Score: 0.0251GO:0009507--chloroplast
Score: 0.0251GO:0042742--defense response to bacterium
Score: 0.0251GO:0009737--response to abscisic acid
Score: 0.0251GO:0009627--systemic acquired resistance
GO terms cooccurrence

Topic #14: Interesting topic
Score: 0.0790GO:0005507--copper ion binding
Score: 0.0757GO:0005886--plasma membrane
Score: 0.0613GO:0005524--atp binding
Score: 0.0398GO:0055114--oxidation-reduction process
Score: 0.0398GO:0016887--atpase activity
GO terms cooccurrence

Topic #15: Interesting topic
Score: 0.0723GO:0009416--response to light stimulus
Score: 0.0723GO:0004970--ionotropic glutamate receptor activity
Score: 0.0723GO:0005217--intracellular ligand-gated ion channel activity
Score: 0.0723GO:0006874--cellular calcium ion homeostasis
Score: 0.0367GO:0030003--cellular cation homeostasis
GO terms cooccurrence

Topic #16: Interesting topic
Score: 0.1257GO:0006979--response to oxidative stress
Score: 0.0843GO:0005886--plasma membrane
Score: 0.0428GO:0003779--actin binding
Score: 0.0428GO:0030041--actin filament polymerization
Score: 0.0428GO:0015031--protein transport
GO terms cooccurrence

Topic #17: Interesting topic
Score: 0.0471GO:0006886--intracellular protein transport
Score: 0.0240GO:0005794--golgi apparatus
Score: 0.0240GO:0005509--calcium ion binding
Score: 0.0240GO:0045892--negative regulation of transcription, dna-templated
Score: 0.0240GO:0015031--protein transport
GO terms cooccurrence

Topic #18: Interesting topic
Score: 0.0672GO:0006508--proteolysis
Score: 0.0229GO:0004252--serine-type endopeptidase activity
Score: 0.0229GO:0012501--programmed cell death
Score: 0.0229GO:0005768--endosome
Score: 0.0229GO:0005618--cell wall
GO terms cooccurrence

Topic #19: Interesting topic
Score: 0.0383GO:0042742--defense response to bacterium
Score: 0.0194GO:0055114--oxidation-reduction process
Score: 0.0194GO:0005829--cytosol
Score: 0.0194GO:0005773--vacuole
Score: 0.0194GO:0005618--cell wall
GO terms cooccurrence

Topic #20: Interesting topic
Score: 0.0520GO:0010468--regulation of gene expression
Score: 0.0264GO:0008270--zinc ion binding
Score: 0.0264GO:0004842--ubiquitin-protein transferase activity
Score: 0.0264GO:0002237--response to molecule of bacterial origin
Score: 0.0264GO:0005829--cytosol
GO terms cooccurrence

Topic #21: Interesting topic
Score: 0.0311GO:0005516--calmodulin binding
Score: 0.0311GO:0005887--integral component of plasma membrane
Score: 0.0311GO:0030553--cgmp binding
Score: 0.0311GO:0030552--camp binding
Score: 0.0311GO:0005249--voltage-gated potassium channel activity
GO terms cooccurrence

Topic #22: Interesting topic
Score: 0.0383GO:0005886--plasma membrane
Score: 0.0257GO:0009751--response to salicylic acid
Score: 0.0257GO:1902290--positive regulation of defense response to oomycetes
Score: 0.0257GO:1900426--positive regulation of defense response to bacterium
Score: 0.0257GO:0006508--proteolysis
GO terms cooccurrence

Topic #23: Interesting topic
Score: 0.1633GO:0046872--metal ion binding
Score: 0.0819GO:0005829--cytosol
Score: 0.0494GO:0055114--oxidation-reduction process
Score: 0.0494GO:0004722--protein serine/threonine phosphatase activity
Score: 0.0494GO:0006979--response to oxidative stress
GO terms cooccurrence

Topic #24: Interesting topic
Score: 0.0343GO:0009737--response to abscisic acid
Score: 0.0343GO:0009414--response to water deprivation
Score: 0.0234GO:0042742--defense response to bacterium
Score: 0.0174GO:0010200--response to chitin
Score: 0.0174GO:0006629--lipid metabolic process
GO terms cooccurrence

Topic #25: Interesting topic
Score: 0.3655GO:0005739--mitochondrion
Score: 0.0494GO:0046983--protein dimerization activity
Score: 0.0251GO:0042631--cellular response to water deprivation
Score: 0.0251GO:0071215--cellular response to abscisic acid stimulus
Score: 0.0251GO:0048573--photoperiodism, flowering
GO terms cooccurrence

Topic #26: Interesting topic
Score: 0.1637GO:0006468--protein phosphorylation
Score: 0.1550GO:0005524--atp binding
Score: 0.1484GO:0005886--plasma membrane
Score: 0.1467GO:0004674--protein serine/threonine kinase activity
Score: 0.0965GO:0004672--protein kinase activity
GO terms cooccurrence

Topic #27: Interesting topic
Score: 0.1121GO:0050832--defense response to fungus
Score: 0.0382GO:0005509--calcium ion binding
Score: 0.0382GO:0009505--plant-type cell wall
Score: 0.0382GO:0007166--cell surface receptor signaling pathway
Score: 0.0382GO:0009615--response to virus
GO terms cooccurrence

Topic #28: Interesting topic
Score: 0.1796GO:0005886--plasma membrane
Score: 0.1278GO:0005524--atp binding
Score: 0.1093GO:0004674--protein serine/threonine kinase activity
Score: 0.1088GO:0006468--protein phosphorylation
Score: 0.0685GO:0004672--protein kinase activity
GO terms cooccurrence

Topic #29: Interesting topic
Score: 0.0612GO:0012501--programmed cell death
Score: 0.0335GO:0009751--response to salicylic acid
Score: 0.0317GO:0004672--protein kinase activity
Score: 0.0315GO:0005886--plasma membrane
Score: 0.0311GO:0005773--vacuole
GO terms cooccurrence